Abstract
Aim. To assess the degree of inflammatory-necrotic destructive process in the body of reproductive age women of with ovarian endometriomas after surgical treatment using different types of energy. Materials and methods. A comprehensive clinical and laboratory examination and surgical treatment by laparoscopic access were performed on 120 women of reproductive age with ovarian endometriomas, of which group I consisted of 60 patients who received intraoperative LOTUS ultrasonic scalpel, group II consisted of 60 patients who underwent bipolar coagulation of ovarian tissues. The examination protocol included an assessment of the clinical course of the postoperative period, indicators of general and biochemical blood tests, including biochemical markers of tissue destruction products. Statistical data processing was performed using a computer program “Statistica 13. 3.721”. Results. The analysis of clinical and laboratory studies in reproductive age women of with ovarian endometriomas revealed a higher effectiveness of the LOTUS ultrasound system compared to bipolar coagulation, as indicated by a 1.3-fold increase in the number of women with a low degree of tissue trauma and a 1.4-fold decrease in the number of women with an average degree of tissue trauma ( p<0.05), a 1.3-fold decrease in patients with leukocytosis, a 1.2-fold decrease in patients with an elevated level of C-reactive protein, a lower content of tissue destruction products in the blood of patients (p<0.05), as well as a 1.2-fold shortening of the postoperative rehabilitation period (p<0.05). Conclusion. Quantitative scoring of surgical trauma in reproductive age women of with ovarian endometriomas objectively demonstrated the effectiveness of intraoperative use of the LOTUS ultrasound system compared to bipolar coagulation of ovarian tissue (p<0.05). The fact of a less traumatic operation when using the LOTUS ultrasound system was confirmed by clinical and laboratory data, including a lower content of tissue destruction products in the blood of patients: MSM 280 by 1.3 times, MSM 254 by 1.2 times, KFNK by 1.2 times, TBK- ap by 1.5 times and a 2.2-fold higher level of ETI (p<0.05)